摘要
目的:探讨血清同型半胱氨酸(homocysteine,Hcy)水平变化在原发性肝癌(primary hepatocarcinoma,PHC)中的临床价值。方法:分析93例原发性肝癌、85例肝硬化患者和50例健康人血清中Hcy、AFP、AFU和GGT水平。结果:原发性肝癌和肝硬化患者血清Hcy水平明显升高,与正常对照组比较均有统计学差异(P<0.05);肝硬化组Hcy随着Child-Pugh分级的升高而递增;治疗前后Hcy水平比较有显著性差异(P<0.05)。结论:同型半胱氨酸水平变化对原发性肝癌肝功能损害程度的判断、疗效监测、预后评估有重要的临床价值。
Objective：To investigate the value of serum homocysteine in primary hepatocarcinoma.Methods：To analyze serum Hcy,AFP,AFU and GGT levels of 93 cases of primary hepatocarcinoma,85 patients with liver cirrhosis and 50 healthy persons.Results：Serum Hcy levels in patients with primary hepatocarcinoma and liver cirrhosis was significantly higher,compared with the control group（P0.05）;Cirrhosis Hcy Child-Pugh increased,Hcy levels before and after treatment were significant different（P0.05）.Conclusion：Homocysteine levels in liver of primary hepatocarcinoma to determine the extent of damage,efficacy evaluation,prognosis has important clinical value.
出处
《现代肿瘤医学》
CAS
2012年第12期2580-2581,共2页
Journal of Modern Oncology
