摘要
相对于T淋巴细胞而言,B淋巴细胞在肿瘤免疫中的研究比较少。B细胞参与肿瘤免疫的可能途径包括三方面:B细胞介导的体液免疫,产生IgG抗体参与肿瘤免疫;B细胞作为抗原提呈细胞参与肿瘤免疫;B细胞对各种免疫细胞进行调节,参与肿瘤免疫。目前越来越多研究显示B细胞在肿瘤免疫领域的重要性,而且B细胞作为肿瘤免疫治疗的靶细胞已开始应用于临床并显示出其广阔的前景。
Less is known about the role of B lymphocyte in tumor immunity when compared to that of T lymphocyte.There are three potential mechanisms：B-lymphocyte-derived autoantibodies promote tumor immunity;B lymphocytes serve as antigen presenting cells and thus play a role;B lymphocytes mediate immunoregulation of various immune cells.More and more reserches demonstrate the importance of B lymphocyte in tumor immunity.And B lymphocytes as target cells prove to be promising immunotherapy against cancer.
出处
《现代肿瘤医学》
CAS
2012年第12期2652-2654,共3页
Journal of Modern Oncology
