摘要
对百两金皂苷类似物的化学和药理活性进行文献综述。迄今报道的百两金皂苷类似物大约有60个,其齐墩果烷三萜母核上具有多种与生物活性有关的特征取代基,包括13β,28-环醚、30-氧化甲基和3-O-糖链等。该类物质多具抗肿瘤、抗炎和抗真菌等药理活性,值得深入研究。
The triterpenoidal analogues of ardisiaerispin reported in the literatures were summarized. There are about 50 triterpenoidal analogues possessing characteristic substituent groups such as 13β,28-epoxy bridge,30-oxidized methyl, and 3-O-glycan chain which were proved necessary to the pharmacological activity. The analogues of ardisiacrispin presented anti-cancer, anti-inflammatory and anti-fungal activities, and they are worth doing further pharmaceutical researches.
出处
《天然产物研究与开发》
CAS
CSCD
北大核心
2012年第11期1671-1679,共9页
Natural Product Research and Development
基金
教育部高等学校博士学科点专项(20104425110014)
