摘要
目的:观察白芍总苷(TGP)联合氯沙坦钾治疗慢性肾炎蛋白尿的作用。方法:选取本院诊断的慢性肾炎患者65例,随机分为2组,治疗组予TGP600mg,每日2次口服;氯沙坦钾100mg,每日1次口服;对照组为氯沙坦钾100mg,每日1次口服。比较两组患者治疗前后的24h尿蛋白定量(UPRO)变化。结果:两组患者治疗前后UPRO均明显下降,差异有统计学意义(P<0.05),而治疗组UPRO较对照组下降的更明显,差异有统计学意义(P<0.05)。结论:白芍总苷联合氯沙坦钾能更有效降低慢性肾炎患者的尿蛋白。
Objective ： To observe the effect of total glucosides of paeony and losartan potassium on proteinuria in patients with chronic kidney disease. Methods：65 cases of chronic kidney disease were divided into two groups, the patients in the treatment group received TPG600mg/d ＋ losartan potassium 100mg/d,the other patients received losartan potassium 100mg/d. The UPRO were measured before and 3 months after the use of TPG and/or losartan potassium. Results ： The proteinuria of the two groups reduced significantly after 3 months （P 〈 0. 05 ）, and the reduction of UPRO in treatment group were higher than in the control group, the difference was statistically significant （P 〈 0.05 ）. Conclusion：Total glucosides of paeony and losartan potassium can reduce the UPRO significantly, and has better therapeutic effects than losartan potassium.
出处
《辽宁中医杂志》
CAS
2012年第12期2440-2441,共2页
Liaoning Journal of Traditional Chinese Medicine
关键词
白芍总苷
氯沙坦钾
蛋白尿
total glucosides of paeony
losartan potassium
proteinuria
