摘要
介绍了纯环肽与杂环肽合成的方法、策略及其优缺点 ,列举了一些常用缩合试剂 ,探讨了反应溶液浓度、线型肽前体化合物的结构及构象等因素对环化反应的影响 .
The synthetic method and strategy of cyclopeptide were presented, some efficient coupling reagents were introduced, and different influence factors such as the concentration of reaction solution, structure of linear peptide precursor, conformation etc, were discussed.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
2000年第7期1056-1063,共8页
Chemical Journal of Chinese Universities
基金
国家自然科学基金! (批准号 :2 9772 0 0 1)资助
