摘要
目的探讨肺炎支原体抗体(MP-IgM)、血清腺苷脱氨酶(ADA)、C-反应蛋白(CRP)、白细胞(WBC)的联合检测对儿童早期感染性肺炎鉴别诊断的价值。方法选取184例诊断为肺炎患儿,其中60例血清MP-IgM阳性,为肺炎支原体感染组,非支原体感染性肺炎患儿124例,MP-IgM阴性,为非肺炎支原体感染组,选取50名正常体检儿童作为对照组,检测3组ADA、CRP及WBC。结果肺炎支原体感染组血清腺苷脱氨酶活性为(32.8±11.2)U/L,明显高于非支原体感染组的(19.6±6.6)U/L及对照组的(18.5±6.9)U/L,差异有统计学意义(P<0.01),非肺炎支原体感染组血清腺苷脱氨酶活性与对照组间差异无统计学意义;非肺炎支原体感染组C-反应蛋白为(13.2～53.6)mg/L,明显高于肺炎支原体感染组的(2.7～15.1)mg/L及对照组的(2.3～13.2)mg/L,差异有统计学意义(P<0.01)。结论同时检测患儿血清ADA、MP-IgM、CRP、WBC水平可作为鉴别诊断肺炎支原体感染的指标。
OBJECTIVE To discuss the value of the joint detection of Mycoplasma pneumonia antibody IgM（MP-IgM）,serum adenosine deaminase（ADA）,C-reactive protein（CRP）,and white blood cell in diagnosis of the early infectious pneumonia in children.METHODS A total of 184 children with infectious pneumonia were enrolled in the study,60 MP-IgM positive children were assigned into the MP infection group,and 124 children without Mycoplasma infection were set as the non-MP infection group,and 50 healthy children were enrolled as the controls.The ADA,CRP and WBC levels were measured.RESULTS The ADA level of the MP infection group was（32.8±11.2）U/L,significantly higher than（19.6±6.6）U/L of the non-MP infection group and（18.5±6.9）U/L of the control group,the difference was statistically significant（P0.001）;there was no statistical difference in the ADA level between the non-MP infection group and the control group;the CRP level of the non-MP infection group was（13.2~53.6）mg/L,significantly higher than（2.7~15.1）mg/L of the MP infection group and（2.3~13.2）mg/L of the control group,the difference was statistically significant（P0.01）.CONCLUSION The ADA,MP-IgM,CRP,and WBC levels may serve as the indicators of the identification of MP infection.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2012年第24期5673-5675,共3页
Chinese Journal of Nosocomiology
