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组织多普勒测定Tei指数在评价高血压患者左心功能中的价值 被引量:4

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摘要 目的应用组织多普勒测定Tei指数评价原发性高血压患者左心功能,探讨其临床应用价值。方法选择经临床证实的原发性高血压患者91例,根据左室质量指数(LVMI)及左室相对室壁厚度(RWT)分为4组:A组21例为正常构型,B组23例为向心性重构,C组25例为向心性肥厚,D组22例为离心性肥厚;另选25例正常人作为对照组。常规超声心动图测量左室射血分数(LVEF),二尖瓣口舒张早期与舒张晚期血流峰值之比(E/A)。组织多普勒成像模式(TDI)下,于心尖四腔、心尖二腔心切面获得前壁、间隔、侧壁和下壁的二尖瓣环频谱曲线,分别计算出4个位点的Tei指数,取平均值。结果 LVEF值在各组之间比较差异无统计学意义(P>0.05),均在正常范围之内,但高血压B、C组升高,D组下降;E/A比值高血压A、B、C组与对照组比较差异均有统计学意义(P<0.05或P<0.01),且B、C组E/A比值下降明显(P<0.01),D组出现假性正常化,与对照组相比差异无统计学意义(P>0.05);高血压各组Tei指数呈递增趋势,各组与对照组比较差异均有统计学意义(P<0.05或P<0.01)。结论 Tei指数能综合、有效、准确地评价高血压患者左室功能,高血压患者在左室肥厚之前就有心功能受损改变,且左室肥厚患者较无肥厚患者损害更明显;对于高血压心肌肥厚LVEF值代偿性增强,E/A比值出现假性正常化,Tei指数可纠正其假阴性。
出处 《实用临床医学(江西)》 CAS 2012年第10期45-46,48,共3页 Practical Clinical Medicine
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