摘要
目的:优选骨炎消巴布剂的基质配方。方法:采用正交设计,选取聚丙烯酸钠(NP-700),羧甲基纤维素钠(CMC-Na),丙三醇和二氧化钛的用量为考察因素,以初黏力、持黏力、综合感官的综合评分为指标,优化骨炎消巴布剂的基质处方。结果:优选的基质处方为NP-700 3 g,CMC-Na 0.6 g,丙三醇16 g,二氧化钛0.8 g。结论:按优选的基质处方制得的骨炎消巴布剂外观、黏附性良好。
Objective： To optimize matrix prescription of Guyanxiao cataplasm. Method： Matrix prescription was optimized by orthogonal test with initial viscosity, sustained adhesive strength and general sensory as comprehensive evaluation index, the amount of NP700, CMC-Na, glycerol and titania were chosen as factors. Result： Optimal matrix prescription was： NP-700, CMC-Na, glycerol and titania of 3, 0.6, 16, 0.8g, respectively. Conclusion： Guyanxiao catapasm with good appearance and adhesion could be prepared by optimized matrix formulation.
出处
《中国实验方剂学杂志》
CAS
北大核心
2012年第24期39-41,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
贵州省中药现代化专项(黔科合中药字[2011]5013号)
贵阳市中药现代化专项([2010]筑科农合同字第1-中13号)
贵阳科技创新公共技术平台项目(2010筑科合同字第3-2)
关键词
骨炎消巴布剂
正交设计
基质处方
Guyanxiao cataplasm
orthogonal design
matrix formulation
