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原发性高血压早期肾损害微量白蛋白尿的临床价值 被引量:18

The clinical value of the relationship between micro-albuminuria and renal defect in early stage hypertension
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摘要 目的 :探讨原发性高血压 (EH)早期肾损害微量白蛋白尿 (U- MAlb)的临床价值。方法 :用免疫透射比浊法对尿蛋白试纸阴性的 16 1例 EH患者测定 U- MAIb,并与 12 5例正常健康者作比较。结果 :EH组 U- MAlb排出量增加的人数占患者的 37.3% ,EH 、 级组极显著高于 级组 , 级组显著高于 级组 ,EH组 U- MAlb极显著高于正常组。结论 :EH患者有相当比例已发生 U- MAlb,高血压级越大 ,年龄越大 ,病程越长 ,发生 U- MAlb的比例越大 ,排出量也越高。定期检测 U - MAlb排出量对发现 EH早期肾损害有重要的临床价值。 Objective:To investigate the clinical value of micro albuminuria (U MAlb) from different degrees of hypertension in early stage.Method:161 patients with hypertension whose urine protein was negative by routine method were detected for U MAlb by immunoturibidmetry assay,and were compared with 125 health people.Result:U MAlb was present in 37.3 % of hypertension group,which was markedly higher than that in normal group (P< 0.001 ).U MAlb in Ⅲ、Ⅳ degree hypertension group was markedly higher than that in Ⅰ degree (P< 0.001 ).U MAlb in Ⅱ degree was statistically higher than in Ⅰ degree (P< 0.05 ).Conclusion:The patients with hypertension had higher percentage of trace albumininuria.The higher the degree of hypertension,the elder the age and the longer the course,the higher the positive percentage of U MAlb.There was important clinical value of detecting periodical U MAlb to find renal damage from hypertension in early stage.
出处 《临床心血管病杂志》 CSCD 北大核心 2000年第6期264-265,共2页 Journal of Clinical Cardiology
关键词 白蛋白尿 高血压 肾损害 Albuminuria Hypertension Renal defect
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