摘要
用正交试验法 ,通过对三七皂苷透皮量的考察 ,发现以氮酮与丙二醇共同作为促透剂 ,且两者用量均为 4 %时 ,三七巴布剂表现出良好的透皮性能 ,2 4h累计透皮率达到 18.0 6 %。
The effects of enhancer on the percutaneous absorption of panax notoginseng cataplasma were investigated in an orthogonal design experiment. The result showed that a two phase enhancer composed of 4% Azone and 4% propylene glycol resulted in good penetration of the drug tested. The cumulative permeation rate within twenty four hours was 18.06%.
出处
《广东药学院学报》
CAS
2000年第2期91-93,共3页
Academic Journal of Guangdong College of Pharmacy
关键词
三七皂苷
巴布剂
氮酮
丙二醇
促透剂
panax notoginseng
cataplasma
Azone
propylene glycol
enhancer
