摘要
探讨深部痰液粒细胞集落刺激因子 (G- CSF)测定对毛细支气管炎合并细菌感染的诊断价值。方法 :采用双抗体夹心 EL ISA法 ,检测 74例单纯毛细支气管炎和 2 7例毛细支气管炎合并细菌感染患儿的深部痰液 G- CSF阳性率 ,并对两组患儿进行痰细菌学培养和病毒病原学检测。结果 :两组 G- CSF阳性率和细菌培养阳性率差异均有显著性 (P<0 .0 1和 P<0 .0 5 ) ,病毒病原学检出率无统计学意义。结论 :痰液G- CSF检测是毛细支气管炎并发细菌感染的敏感性指标。
Objective:To explore the diagnostic value of granulocyte colony stimulating factor(G CSF) in the nasopharyngeal secretions (NPS) of bronchiolitis complicated with bacterial infection in infancy.Methods:The level of G CSF in NPS was determined by ELISA in 74 cases of bronchiolitis without complications and 27 comlicated with bacterial infection.Bacterial culture and viral detection were performed in 50 randomly selected cases.Results:The positive rate of G CSF and bacterial culture in bronchiolitis complicated group was apparently higher than that the group without comlication (P<0.01 and P<0.05,respectively) and the viral detection rate showed no statistical significance between two groups (P>0.05).Conclusion:G CSF in NPS is a sensitive and feasible index to evaluate the bronchiolitis complicated with bacterial infection.
出处
《温州医学院学报》
2000年第2期112-113,共2页
Journal of Wenzhou Medical College
关键词
毛细支气管炎
痰液
G-CSF
细菌培养
病原学
bronchiolitis
nasopharyngeal secretions
granulocyte colony stimulating factor
bacterial culture
viral detection
