摘要
目的 研究地氟醚复合麻醉对冠心病高危因素病人自主神经系统功能的影响。方法 30例择期腹部手术病人 ,术前确诊为冠心病高危人群。用动态心电图仪记录诱导前、呼气末地氟醚浓度在 0 5、1 0、1 5、2 0MAC时的心率变异性。结果 在低浓度地氟醚麻醉下低频功率明显高于基础值 (P <0 0 5 ) ;随着吸入浓度增加 ,低频、高频功率均下降 (P <0 0 5 ) ;LF/HF比值与基础值相比无明显变化 (P >0 0 5 )。结论 地氟醚复合麻醉使自主神经活性呈进行性抑制 ,在辅用氧化亚氮。
Objective To investigate the effect of desflurane anesthesia on the autonomic nervous system in patients at high risk for coronary artery disease.Methods Thirty patients at high risk for coronary artery disease scheduled for elective abdominal operation were selected. Heart rate variability (HRV) was assessed at preoperation, inhalation of 05,10,15 and 20 MAC of desflurane with Holter electrocardiography Results Low-frequency component increased markedly inhaling low concentration of desflurane. With the increase of the concentration of desflurane, both the high-frequency and low-frequency components decreased significantly (P<0 05); the ratio of low-frequency component to high-frequency component did not change significantly during desflurane anesthesia comparing with the preoperative value (P>0 05).Conclusions Desflurane balanced anesthesia dose not increase the activity of sympathetic nervous system.
出处
《中华麻醉学杂志》
CAS
CSCD
北大核心
2000年第3期149-151,共3页
Chinese Journal of Anesthesiology
关键词
地氟醚
复合麻醉
心率变异性
冠心病
Desflurane
Coronary artery disease
Heart rate variability
Myocardial ischemia
