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45例听神经病的临床与听力学分析

Clinical and Audiological Analysis of 45 Cases of Auditory Neuropathy
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摘要 目的探讨听神经病的临床与听力学特征。方法分析45例听神经病患者的临床资料、纯音听阈、声导抗测试、听性脑干反应ABR、40Hz-听觉相关电位、瞬态耳声发射和畸变产物耳声发射及对侧白噪声抑制试验的检查结果。结果纯音听阈示低频下降型感音神经性听力损失,以250Hz处听力损失最重。声导抗鼓室图全部正常,镫骨肌声反射84耳未引出,6耳部分反射阈提高。ABR波Ⅰ全部未引出。40Hz-听相关电位87耳正常引出,阈值升高。全部病例可记录到OAE,不能被对侧噪声抑制,个别高频幅值DPOAE升高。结论听力图多为上升型,低频损失为主,EOAE正常,而ABR严重异常,言语分辨力差与纯音听阈不成比例,镫骨肌声反射及EOAE交叉抑制异常,是听神经病的重要听功能特征。提示病变位于内毛细胞或听神经。 Objective To study the clinical and auditory characteristics of auditory neuropathy.Methods The clinic signs,pure tone audiometry,stapedial reflex,auditory brainstem response(ABR),40Hz auditory event related potential(40Hz AERP) and otoacoustic emissions(OAEs),and contralateral suppression of white noise.Results The pure tone audiogram showed a sensor ineural hearing loss at low frequencies 250Hz.stapedial reflex was absent in 84 ears,and threshold elevated in 6 ears.Auditory brainstem responese can’t be recorded from wave I.87 ears had normal 40Hz-AERP.all of the patients were evoked a distortion product OAE,which can’t be suppressed by contratateral while noise.Conclusion Lose of the pure tone threshold primarily in kow frequency SNHL unparalld pure tone threshold tispeech eudiomertry,abnormal ABR,normal EOAE,loss of stapedial acoustic reflex and OAE contra acoustic supperssionare are important feaioures of AN which shows thatlesionsd site may lie at the cochlear inter hair cells or acoustic nerve.
作者 刘丽岱 丁春
出处 《中国医药指南》 2012年第33期141-142,共2页 Guide of China Medicine
关键词 听神经病 感音神经性 听力损失 Auditory neuropathy Sensorineual Hearing loss
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