摘要
目的:运用斑点成像技术矩阵取样的方法在左心室前壁心肌额断面上,分析左室前壁心肌上25个感兴趣区(ROIs)的应变与应变率,观察左心室前壁缺血时左心室前壁额断面局部心肌功能的变化。方法:选择左心室前壁缺血(缺血组)患者及无左心室前壁缺血(对照组)的患者各20例,在左心室前壁心肌额断面超声采集25个ROIs的斑点追踪所获的收缩期应变(ε)、收缩期应变率(SRS)、舒张早期应变率(SRE)及舒张晚期应变率(SRA),比较两组患者应变及应变率的差异,并以对照组SRS、SRE及SRA的95%医学参考值范围作为阈值参考,计算缺血组异常ROIs的百分率(PAR)。结果:25个ROIs的斑点追踪测得缺血组SRS与SRE均小于对照组(P<0.05);以对照组应变率的测量值制定95%医学参考值范围为基准参数,观察到缺血组的左心室前壁心肌SRS与SRE低于对照组基准水平18.66%～25.35%。结论:应用左心室前壁心肌额断切面以矩阵采样的方式,采集25个ROIs的斑点追踪局部左室功能参数,通过心肌异常位点的检出率(PAR)能够检测出左心室前壁心肌缺血患者的局部心肌功能异常。
Objective：To measure myocardial strain and strain rate in a multiple sampling way at coronal plane of left ventricle （LV） in patients with ischemia in the anterior wall （AW） of LV using two-dimensional and speck- le-tracking echocardiography （STE）. Method：Patients with or without myocardial ischemia in the AW of LV were selected （20 patients for each group）. Twenty-five regions of interest （ROIs） on the AW were displayed and tracked by STE. Variability of the strain （e）, strain rates in systole （SRS）, strain rates in early-diastole （SRE）, strain rates in late-diastole （SRA） were recorded. ε, SRS, SRE and SRA of the group without ischemia AW of LV were consideraded as 95% medical reference range for normal wall motion and percentage of abnormal ROIs （PAR） were calculated. Parameters under the reference were considered abnormal. Result..~, SRS and SRE by 25 ROIs of STE were siginificantly decreased in group of ischemia in the AW （P〈0.05）. PAR of ε, SRS and SRE in group of i schemia of the AW were from 18.66% to 25.35 % as evaluated by reference in the control. Conclusion： Twenty-five sampling ROIs at coronal plane of LV in patients could be a valuable modality for detention of regional wall abmormal in paitents with normal global LV funcution.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2012年第12期901-904,共4页
Journal of Clinical Cardiology
基金
浦东新区科技发展基金创新资金(No:PKJ2010-Y16)
上海市卫生局青年基金(No:2010Y012)
上海市浦东新区心血管疾病学科群项目(No:PWZxkq2010-01)
上海市卫生局卫生科技面上项目(No:2009158)
