摘要
目的研究婴幼儿反复呼吸道感染发病机制中相关因素。方法选取60例反复呼吸道感染的患儿作为实验组治疗前后对应为急性期,缓解期,同时选取50例健康体检儿童作为对照组,检测免疫球蛋白、急性时相反应蛋白,血清微量元素等三大类项目。结果 (1)IgG急性期与缓解期对比t=3.53,与对照组t=5.12,IgA急性期水平均显著低于对照组水平t=3.20,缓解期与对照组t=2.67。P均<0.05;(2)急性期铁锌钙含量低于对照组t>4.0均P<0.01(3)急性期c3,CRP水平明显高于对照组。结论 IgA水平低下,铁锌钙含量减低与反复呼吸道感染发作相关;急性时相蛋白异常与病情有密切关系。
Objective To study the related factors causing infants recurrent respiratory tract infection. Methods 60 infants with recurrent respiratory tract infections were selected as the experiment group, and the time before and after the treatment were defined as the acute stage and the remission stage respectively. At the same time, the study selected 50 healthy infants as the control group. The immunoglobulin, reactive protein at the acute stage, and trace elements in serum were detected and analyzed. Results （ 1 ） The IgG contrast of the acute stage to the remission stage was t = 3.53, and to the control group was t = 5.12. The level of IgA was significant lower at the acute stage than at the remission stage and the control group （P 〈 0. 05 ） ; （2） The content of iron, zinc and calcium was lower in the acute stage than in the control group （ t 〉 4.0, P 〈 0. 01 ） ; （ 3 ） The level of C3 and CRP was significantly higher at the acute stage than at the control group. Conclusion The low level of IgA and the content reduction of iron, calcium and zinc are related to recurrent respiratory tract infection; and the high level of C3 and CRP in acute stage has a close relationship with patients＇ condition.
出处
《临床肺科杂志》
2013年第1期66-67,共2页
Journal of Clinical Pulmonary Medicine
关键词
反复感染
免疫功能
急性时相
recurrent infection
immunologic function
acute stage
