摘要
目的分析2010年河南省开展麻疹减毒活疫苗(Measles Attenuated Live Vaccine,MV)强化免疫活动(SupplementaryImmunization Activity,SIA)后,疑似预防接种异常反应(Adverse Events Following Immunization,AEFI)的发生特征,探讨MV SIA的安全性。方法采用描述性方法对相关指标进行流行病学分析。结果 2010年河南省MV SIA活动共报告AEFI 872例,发生率4.31/10万剂;男性多于女性。>80%的AEFI出现在接种后<2 d;临床损害以红肿、发热和过敏性皮疹等为主;绝大多数病例预后良好。结论 MV SIA的AEFI监测敏感性高,疫苗安全性良好,接种对象在接种MV后<2 d是监测的重点。
Objective To analyze the characteristics and regular patterns of adverse events following immunization （ AEFI ）after supplementary immunization activity （SIA）of Measles attenuated live vaccine （MV）in Henan province in 2010, and to discuss the safety of MV SIA. Methods The descriptive epidemiology analysis on related indexes were conducted. Results 874 cases of AEFI were reported in MV SIA in 2010. The incidence rate was 4.31 per 100, 000 doses, and male was higher than female; more than 80% AEFI occurred within 2 days after vaccination. Allergic reaction is the main reaction of vaccination. Most of the cases were cured. Conclusions Surveillance of AEFI following MV SIA within 2 day after vaccination is the priority population. The sensitivity of the surveillance system is high, MMV is safe.
出处
《河南预防医学杂志》
2012年第6期444-447,共4页
Henan Journal of Preventive Medicine
关键词
麻疹减毒活疫苗
强化免疫活动
疑似预防接种异常反应
发生率
监测
Measles and Mumps combined attenuated live vaccine
Supplementary immunization activity
Adverse events followinimmunization
Incidence
Surveillance
