摘要
双八面体蒙脱石干混悬剂 ( Dioctahedral Sm ectite for Suspension,DSS) ( 8,4 g/ kg,po) ,对大黄液所致小鼠腹泻有显著止泻作用 ( P<0 .0 1) ;可显著延缓脾虚小鼠的黑粪排出时间 ( P<0 .0 1) ;可显著抑制由新斯的明产生的小鼠小肠推进机能亢进作用 ( P<0 .0 1) ;可显著抑制脾虚小鼠小肠推进功能 ( P<0 .0 1,P<0 .0 5) ;对正常小鼠小肠推进功能无明显影响。DSS( 4 ,2 g/ kg)对连续 po番泻叶液一个月的慢性腹泻大鼠有显著止泻作用 ( P<0 .0 1,P<0 .0 5)
Dioctahedral Smectite Suspension (DSS) (8,4 g/kg,po) has significant antidiarrheal effect on diarrhea of mouse induced by Rheum solution ( P <0.01); DSS can elongate the black faeces dejection time of splenic insufficiency mouse ( P <0.01); it also has marked inhibitive effect on hyperfunction of propulsion in mouse intestine induced by neostigmine ( P<0.01,P <0.05); but no great effect was produced on normal mouse. DSS (4,2 g/kg)has shown dominant antidiarrhea effect on the chronic diarrhea rats resulting from one month continuous po.administration of \%cassia angustifolia\% extraction.
出处
《中国药科大学学报》
CAS
CSCD
北大核心
1999年第6期448-450,共3页
Journal of China Pharmaceutical University
