摘要
目的评价解郁安神颗粒合并米氮平治疗持续性躯体形式疼痛障碍的临床疗效。方法将84患者随机分为两组,研究组以解郁安神颗粒合并米氮平治疗,对照组单用米氮平治疗,治疗8周,采用抑郁自评量表(SDS)、焦虑自评量表(SAS)、临床疗效总评量表(CGI)、副反应量表(TESS)及医学结局研究用疼痛量表(MOSPM)评定。结果研究组与对照组疗效相仿,但研究组的不良反应明显小于对照组(P<0.01)。结论解郁安神颗粒合并米氮平不失为治疗持续性躯体形式疼痛障碍的有效方法,且不良反应少,值得临床推广应用。
Objective To evaluate Jieyu granule combined with mirtazapine in the treatment of persistent somatoform pain disorder clinical curative effect. Methods 84 patients were randomly divided into two groups, the study group with Jieyu granule combined with mirtazapine treatment, the control group only with mirtazapine treatment, treatment for 8 weeks, the Self-rating Depression Scale (SDS) , Self-rating Anxiety Scale (SAS) , clinical global impression (CGI) , side reaction table (TESS) and the medical outcomes study pain scale (MOSPM)assessment. Results the study group and the control group effects were similar, but the study group of the adverse reactions were significantly lower than that of control group ( P 〈 0. 01 ). Conclusion Jieyu granule combined with mirtazapine is regarded as the treatment of persistent somatoform pain disorder effectively, and it has less adverse effects, it is worthy of clinical application.
出处
《光明中医》
2012年第6期1205-1207,共3页
GUANGMING JOURNAL OF CHINESE MEDICINE