期刊文献+

KDIGO指南解读:狼疮性肾炎治疗 被引量:11

Treatment of lupus nephritis:interpretation of KDIGO guideline
原文传递
导出
摘要 狼疮性肾炎(LN)在我国发病率相对较高,患者个体差异大,同时各医疗中心的治疗选择不尽相同,不利于LN患者的规范化治疗。2011年,国际改善全球肾脏病预后组织(KDIGO)颁布的肾小球肾炎临床诊疗指南,对LN的治疗在组织病理分型基础上做了详细的阐述。本文以KDIGO指南为基础,结合临床实际以及其他组织新发布的指南,就中国LN患者的一般治疗及免疫抑制治疗提出新的解读。 Summary:The 2011 Kidney Disease: Improving Global Outcome (KDIGO) guideline has delineated the treatment of lupus nephrits (LN) based on pathological classification of glomerulonephritis. The comparatively high prevelence of LN, varying between-individual difference and various treatment protocols among institutions in China may have hampered standarization of therapy. On the basis of KDIGO guideline,the present review targeted at interpreting general treatment protocols and ad- ministration of immunosuppressants in Chinese patients with LN by means of integrating with routine clinical practice and latest guidelines released by miscellaneous organizations.
作者 付平 秦伟
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2012年第12期921-924,共4页 Chinese Journal of Practical Internal Medicine
关键词 KDIGO指南 狼疮性肾炎 系统性红斑狼疮 KDIGO guideline lupus nephritis systemic lupus erythematosus
  • 相关文献

参考文献13

  • 1Seligman VA, Lum RF, Olson JL, et al. Demographic differences in the development of lupus nephritis:A retrospective analysis [ J 1. Am J Med,2002,112(9) :726-729.
  • 2Sis6 A, Ramos-Casals M, Bov A, et al. Previous antimalarial therapy in patients diagnosed with lupus nephritis: influence on outcomes and survival [J]. Lupus,2008.17(4):281 -288.
  • 3Bertsias GK,Tektonidou M, Amoura Z,et al. Joint European League Against Rheumatism and European Renal Association-European Di- alysis and Transplant Association ( EULAR/ERA-EDTA ) recom- mendations for the management of adult and paediatric lupus nephri- tis [J]. Ann Rheum Dis,2012 Jul 31 [ Epub ahead of print].
  • 4Austin HA 3rd, Klippel JH, Balow JE, et al. Therapy of lupus ne- phritis. Controlled trial of prednisone and cytotoxic drugs [ J ]. N Eng J Med,1986. 314(10) :614 -619.
  • 5Chan TM, Li FK, Tang CS, et al. Efficacy of mycophenolate mofetil in patients with diffuse proliferative lupus nephritis [ J ]. N Eng J Med ,2000,343 ( 16 ) : 1156 - 1162.
  • 6Appel GB, Contreras G, Dooley MA, et al. Mycophenolate Mofetil versus Cyclophospharnide for Induction Treatment of Lupus Nephritis [ J 1. J Am Soc Nephro1,2009.20 ( 5 ) : 1103 - 1112.
  • 7Wang HY, Cui TG, Hou FF, et al. Induction treatment of prolifera- tive lupus nephritis with leflunomide combined with prednisone: a prospective multi-centre obsmwational study [ J 1. I,upus, 2008,17 (7) :638 -644.
  • 8Contreras GPV, Leelercq B, Lenz O, et al. Sequential therapies for proliferative lupus nephritis [ J 1. N Eng J Med, 2004,350 ( 10 ) : 971 - 980.
  • 9Moroni GDA, Mosea M,Alberighi ODC, et al. A randomized pilot tri- al comparing cyclosporine and azathioprine for maintenance in dif- fuse lupus nephritis over four years [ Jl. Clin J Am Soc Nephrol, 2006,1 (5) :925 -932.
  • 10Austin HAt, IG, Braun MJ, Balow JE, Randomized, controlled trial of prednisone, cyclophosphamide, and cyclosporine in lupus mem- branous nephropathy [ .1 ]. J Am Soc Nephro1,2009,20 (4) :901 - 911.

同被引文献121

引证文献11

二级引证文献74

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部