摘要
目的探讨胸段食管癌术后淋巴结转移情况及术后放疗效果。方法选取65例胸段食管癌患者,胸上段14例,胸中段27例,胸下段24例;发生淋巴结转移者38例,病灶大小:<3 cm者35例,≥3 cm者30例,所有患者均采用食管癌根治术配合术后放疗,回访3年,观察65例患者治疗转归及不同部分胸段食管癌淋巴结转移特点及术后放疗疗效,对病灶大小及有无淋巴结转移与患者术后1、3年生存率的关系进行分析。结果 65例患在者采用食管癌根治术联合术后放疗后,60例(92.31%)肿瘤得到一定程度的控制,回访3年期间,1年生存率为76.92%(50/65),3年生存率为58.46%(38/65)。胸上段食管癌淋巴结转移以颈部淋巴结转移多见,胸中段及胸下段食管癌以腹腔淋巴结及纵隔淋巴结多见,且胸中段食管癌患者术后1年生存率及3年生存率均明显高于胸上段及胸下段食管癌。病灶<3 cm及无淋巴结转移的患者术后1、3年生存率均显著高于病灶≥3 cm及发生淋巴结转移的患者,P<0.05。结论胸段食管癌术后易发生淋巴结转移,术后联合放疗,可提高患者术后生存率,改善患者预后,提高患者生活质量,是胸段食管癌患者术后发生淋巴结转移重要的有效的治疗手段。
Objective To investigate the efficacy of lymph node metastasis and postopera- tive radiotherapy after thoracic esophageal cancer surgery. Methods Sixty-five thoracic esophageal cancer patients were included in the study, including chest on paragraph （14 cases）, chest para- graph （27 cases） and chest lower segment （24 cases）. Lymph node metastasis occurred in 38 cases with no lymph node metastasis in 27 cases. The sizes of lesions include： 35 cases 〈3 cm and 30 cases ≥3 cm. All patients had esophageal cancer radical surgery with postoperative radiotherapy. A follow-up was conducted for 3 three years to observe the characteristics of 65 patients in treatment outcome, thoracic lymph node metastases and postoperative radiotherapy. The relationship between the lesion sizes with or without lymph node metastasis, and one-year and three-year survival rates of patients were analyzed. Results Sixty-five patients received esophageal cancer surgery combined with postoperative radiotherapy. The tumor in 60 cases （92.31% ） was controlled with varying de- grees. The results of the 3-year follow-up revealed that 1-year survival rate was 76.92% （50/65）, and the 3-year survival rate was 58.46% （38/65）. Upper thoracic lymph node metastases were more common than cervical lymph node metastasis, and the middle thoracic and lower thoracic esophageal cancer were more common in the abdominal lymph nodes and mediastinal lymph nodes. Postoperative 1-year survival and 3-year survival rate were higher in esophageal cancer patients with higher section and the lower thoracic esophageal cancer in the chest . The postoperative 1 - year survival and 3-year rates were higher in patients with lesions 〈 3 cm and without lymph node metastasis than in patients with lesions 93 cm. Conclusion Lymph node metastasis is common- ly seen in patients after thoracic esophageal cancer surgery. The combined radiotherapy can im- prove the survival rate, prognosis and life quality of patients. Thus, it is an important treatment method.
出处
《实用临床医药杂志》
CAS
2012年第22期73-75,共3页
Journal of Clinical Medicine in Practice
关键词
胸段食管癌
淋巴结转移
放疗
预后
thoracic esophageal cancer
lymph node metastasis
radiotherapy
prognosis
