摘要
目的:对比分析3种七氟烷吸入诱导方式,筛选出较为理想的七氟烷全麻诱导方法。方法:60例ASAⅠ～Ⅱ级,aningg患者均在术的随机分为3组,每组20例:肺活量呼吸法(A)组、潮气量呼吸法(B)组和逐渐增加浓度法(C)组。观察诱导期间患者的血压、心率、意识及不良事件发生情况,并统计分析。结果:3组患者诱导前差异无统计学意义(p>0.05);麻醉诱导后,3组各时点血压均有所下降,T3、T5和T6时点与T1差异有统计学意义(p分别<0.01和0.05);A组T3时点HR与T1差异有统计学意义(p<0.05),C组T3时点HR与T2差异有统计学意义(p<0.05);3组同一时点BP和HR组间差异均无统计学意义;A组病人睫毛反射消失时间明显短于B组(p<0.05)与C组(p<0.01),且B组明显短于C组(p<0.05);3组患者不良事件发生率无统计学差异(p>0.05)。结论:3种七氟烷吸入诱导方法均安全、可靠,肺活量法诱导时间最短,血流动力学稳定,并不增加不良事件发生率,是一种较理想的麻醉诱导方法。
Objective： To investigate the patients with variety inhalation methed and inhalation concentration during sevoflurane induction of general anesthesia, To select the ideal methed of sevoflurane induction of general anesthesia. Methods：Sixty patients with ASA I ~ II were randomly divided into three groups,every group included twenty patients.Vital capacity breathing（group A）;Tidal capacity breathing（group B）;gradually increased concentration（group C）. we measured and recorded blood pressure（BP）,heart rate（HR）. recored the time of loss of eyelash reflex.The incidence of adverse events during the induction were recored too.SPSS11.5 software was used as statistical method.Results： Before induction,all mean values are normal range.Between groups.there were no significance（p 〉 0.05）;After induction,all values compared in the same group, BP values decreased than T1 in the other points,T3（p 〈 0.01）decreased greatly significant;T5,T6（p 〈 0.05）decreased significant; Group A,Comparison with T1,Htk decreased ,T3 decreased significant（p 〈 0.05）; Group C：Comparison with T1, Htk increased slightly at T2 point, T3 decreased greatly, T3 decreased significant than T2（p 〈 0.05）. Comparison with groups：All the values were no significance.Between groups, the time of loss of eyelash reflex were significant（p 〈 0.05）, group C was greatly significant than group A（p 〈 0.01）. The incidence of adverse events were no significance（p 〉 0.05）.Conclusion： Inhalation induction of anaesthesia with sevoflurane with the three techniques tested should be safe,reliable;The vital capacity inhalation induction group with sevoflurane was the fastest methed.Comparison with two groups,the effect of hemodynamic changes was no significance,it was not increased the ratio of the incidence of adverse events.So it might be the ideal methed of sevoflurane induction of general anaesthesia.
出处
《中国伤残医学》
2012年第12期12-14,共3页
Chinese Journal of Trauma and Disability Medicine
关键词
七氟烷
麻醉
诱导
吸入
Sevoflurane
Anaesthesis
Induction
Inhalation
