摘要
目的探讨纳米银创伤贴的皮肤刺激性刺激及变态反应。方法将纳米银创伤贴用于家兔背部完整或破损去毛区皮肤,观察其产生皮肤刺激性情况;采用致敏与激发接触纳米银创伤贴,观察豚鼠过敏情况。结果纳米银创伤贴未产生皮肤刺激性;反复致敏后无皮肤与全身变态反应。结论纳米银创伤贴是安全的新型外用贴剂。
Objective To explore the skin irritation and skin allergy reaction of Nano Silver band-aid.Methods Nano Silver band-aid was spread on the integral and damaged skins that hairs were cut off in the back of rabbit.It was observed whether Nano Silver band-aid could induce skin irrita tion.The allergy reactions of guinea pigs were watched by sensitizing and challenge contact to Nano Silver band-aid.Results The results indicated that Nano Silver band-aid did not induce acute skin irritation,and did not cause skin and whole body allergy reaction by many times sensitization.Conclusion Nano Silver band-aid is a newly preparation which can be used safely and handily.
出处
《中国当代医药》
2012年第36期10-11,共2页
China Modern Medicine
关键词
纳米银创伤贴
皮肤刺激性
皮肤变态反应
试验
Nano Silver band-aid
Skin irritation
Skin allergy reaction
Experiment
