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纽甜及其中间体3,3-二甲基丁醛的合成研究进展 被引量:2

Recent progress about synthesis of neotame and 3,3-dimethybutyraldehyde
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摘要 作为阿斯巴甜的N-烷基化衍生物的纽甜具有甜度高、热量低、稳定性好等优良特性,是众多甜味剂中性能最优异的一种,在我国具备一定的市场竞争力,具有较好的发展前景。本文对非营养型强力甜味剂纽甜的性质和应用进行了简单评述。主要讨论了以阿斯巴甜为前体的纽甜及其关键中间体3,3-二甲基丁醛的合成方法,着重分析了非均相催化氢化法合成纽甜和氧化法合成3,3-二甲基丁醛,并且对TEMPO催化醇氧化的方法进行了展望。 Neotame, a derivative of aspartame has high - sweetness, is low - calorie and high - stability and its prop- erty is the best among sweeteners. Therefore, neotame has certain market competitiveness and excellent growth prospects. In this article, the properties and applications of neotame were reviewed in general. The synthesis methods of neotame from its precursor aspartame as well as its important intermediate 3, 3 - dimethybutyaldehyde was discussed. The discusses was focused on homogeneous catalysis method and the oxidation method to synthesize 3, 3 - dimethybuty- aldehyde. Morever, oxidation of 3, 3 -dimethybutanol used TEMPO as catalyst was prospected.
出处 《中国食品添加剂》 CAS 北大核心 2012年第6期230-236,共7页 China Food Additives
关键词 纽甜 合成 3 3-二甲基丁醛 甜味剂 synthesis neotame 3, 3- dimethybutyraldehyde sweetener
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