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鸣禽前脑听觉和鸣唱系统zenk基因的诱导表达 被引量:3

Song and Singing-induced zenk Gene Expression in Auditory and Song System of Songbird Forebrain
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摘要 鸣曲和鸣唱行为可以诱导鸣禽前脑不同区域的zenk基因表达.鸣禽听到同类鸣曲时在听觉系统会出现zenk表达,并在致聋后这种诱导消失.而鸣禽鸣唱时,在鸣唱系统同样有zenk基因的表达,且不依赖于听觉反馈,因为致聋鸟只要发声就可以诱导表达.大量的研究表明,zenk基因在听区的诱导表达不仅可对同类鸣曲进行识别,而且在教习曲模板的记忆方面发挥重要作用.鸣唱系统zenk基因诱导表达则主要与鸣曲的产生与维持有关.zenk基因在两个系统中的诱导表达将听觉感知与鸣唱运动紧密联系起来. Song and singing can induce zenk gene expression in different areas of a songbird's forebrain.zenk gene was rapidly activated in the brain of a songbird by conspecific song,which would disappear after deafening.Moreover,the act of singing induced zenk gene expression in song nuclei,which was independent of auditory feedback.Evidence has suggested that zenk gene expression in auditory system is associated with recognition of birdsong and memory of tutor song.zenk gene expression in song system is also related to song production and maintenance.Thus,zenk gene expression is involved in not only the auditory system but also the song system.
出处 《生命科学研究》 CAS CSCD 北大核心 2012年第6期551-556,564,共7页 Life Science Research
基金 国家自然科学基金资助项目(31172092)
关键词 zenk基因 诱导表达 听觉系统 鸣唱系统 鸣禽 zenk gene expression auditory system song system songbirds
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