摘要
急性肝衰竭(acute hepatic failure,AHF)是一种严重的临床综合征,其特征是肝功能损伤迅速、肝性脑病的发生、多器官衰竭及多数情况下脑水肿的出现,其病死率极高.目前药物治疗、人工肝和肝移植的快速发展,AHF治疗效果有明显提高,但是由于其病因复杂,病情进展迅速,临床研究较少,对于AHF的治疗一直缺乏有效的方案.因此,AHF的有效治疗仍是临床亟待解决的问题,本文就AHF的治疗做一综述.
Acute hepatic failure （AHF） is a devastating clinical syndrome characterized by rapid im- pairment of liver functions and development of encephalopathy, multiple organ failure, and in most cases cerebral edema. AHF has a high mor- tality rate. Although advances in drug treatment, artificial liver and liver transplantation have sig- nificantly improved the prognosis of AHF, there is still a lack of effective treatment for AHF be- cause of its complicated etiopathogenesis, rapid progression and less clinical knowledge about managing the disease. There is an urgent need to develop effective treatments for AHF. This ar- ticle aims to review recent advances in the treat- ment of AHF
出处
《世界华人消化杂志》
CAS
北大核心
2012年第33期3237-3243,共7页
World Chinese Journal of Digestology
关键词
急性肝衰竭
治疗
抗病毒
人工肝
肝移植
Acute hepatic failure
Treatment
Anti-virus
Artificial liver
Liver transplantation
