摘要
目的 观察降纤酶对急性缺血性脑血管病的临床疗效。 方法 根据随机数字表分治疗组 2 6例 ,注射降纤酶首剂量 1 0 u加入生理盐水 1 0 0 ml静脉滴注 ,其后 5u隔日静脉滴注 ,共用 3次 ,总量 2 0 u,观察期间用药与对照组相同。对照组 1 2例 ,应用低分子右旋糖酐 50 0 ml加丹参注射液 1 2～ 2 4 g静脉滴注 ,连续用 1 4天。观察指标为神经功能缺损评分、日常生活能力及临床疗效。 结果 治疗组与对照组治疗前后神经功能缺损评分及日常生活能力无显著性差异 ,临床疗效治疗组显效率显著高于对照组 ,两组之间有极显著性差异。 结论 降纤酶是治疗脑梗死的理想药物。
Objective To assess the efficacy and safety of Defibrase in patients with cerebral infarction Methods 38 patients were randomized to receive either defibrase or placeto,clinical assessments were undertaken at 2 and 3 weeks after treatment with Scandinavian stroke scale(SSS) and Activities of Daily Living(ADL) Results For the SSS and ADL,there were no significant difference between the two groups before and after treatment,But the clinical outcomes was much better in the Difibrase group No toxic effects was found Couclusion Defibrase may be effective and safe drug in the treatment of cerebral infarction
出处
《蛇志》
2000年第1期28-29,共2页
Journal of Snake
关键词
脑梗死
常规药物
降纤酶
疗效试验
cerebral infarction,defibrinogen drugs,defibrase,treatment
