摘要
目的评价液基细胞学联合人乳头状瘤病毒(HPV)-DNA检测对宫颈癌筛查的临床价值。方法采用液基细胞学联合HPV-DNA筛查方法和宫颈活检方法对宫颈鳞状上皮内高度病变(HSIL,CINⅡ～Ⅲ)和鳞状细胞癌(SCC)进行筛查,比较两种方法的筛查准确性。结果液基细胞学共筛查1 465例,与宫颈活检诊断符合率:鳞状细胞癌(SCC)100%(7/7)、鳞状上皮内高度病变(HSIL)78.9%(30/38)、鳞状上皮内低度病变(LSIL)83.3%(35/42)、不典型鳞状细胞(ASCUS)72.9%(97/133)。HPV16、18感染表现随宫颈病变加重而逐渐升高。结论液基细胞学联合HPV-DNA检测对宫颈癌的筛查准确性高,是一种较为理想的宫颈癌筛查方法。
Objective To evaluate the clinical value of hquid -based cytologic screening combined with human papillomavims -DNA in detecting cervical carcinoma. Methods We used LB cytologic and HPV methods to detect the samples. The accuracy of two methods was compared. Results The co- incidental rate between these methods and biopsy was ：SCC100% （7/7） ,HSIL78.9% （ 30/38 ） ,LSIL83.3% （35/42）, ASCUS 72.9% （97/133）. The infection of HPV16, 18 in cervical lesions increased gradually with increased performance. Conclusion Autocyte prep LCT and HPV measurement are the good methods for screening cervical carcinoma.
出处
《临床和实验医学杂志》
2013年第2期118-119,共2页
Journal of Clinical and Experimental Medicine
关键词
宫颈癌
液基细胞学
人乳头状瘤病毒
Cervical carcinoma
Liquid-based cytology
Human papillomavirus
