摘要
目的调查2型糖尿病患者阻塞性睡眠呼吸暂停综合征(OSAS)患病情况,并分析其相关特点。方法选择2型糖尿病患者213例,使用便携式睡眠呼吸监测仪调查睡眠呼吸情况。分析OSAS患病状况、严重程度,并分析其相关因素。最终完成睡眠呼吸监测共145例。根据诊断分为OSAS组114例和非OSAS组31例。结果与非OSAS组比较,OSAS组患者体重指数、腰围、糖化血红蛋白、高血压及冠心病患病率明显升高(P<0.01)。糖化血红蛋白与OSAS患病风险独立相关(OR=6.24,95%CI:2.21～9.23,P<0.01)。糖化血红蛋白、体重指数、高血压、年龄、糖尿病病程与呼吸暂停低通气指数独立相关,糖化血红蛋白是主要的独立危险因素。结论 2型糖尿病患者OSAS患病率较高,血糖控制差者OSAS发病风险高,且病情更为严重,肥胖、年龄大、病程长或合并高血压者OSAS较为严重。
Objective To investigate the prevalence of obstructive sleep apnea syndrome（OSAS） in patients with type 2 diabetes mellitus and its related factors. Methods Prevalence and severity of OSAS and its related factors were analyzed in 213 type 2 diabetes mellitus patients who used a portable OSAS monitoring device. Of the 145 patients（109 males and 36 females）who completed their OSAS monitoring were divided into OSAS group （n = 114） and non-OSAS group （n = 31 ）. Results The body mass index,waist circumference,hemoglobin Alc level,and the incidence of hy- pertension and coronary heart disease were significantly higher in OSAS group than in non-OSAS group（P〈0.05）. The hemoglobin Alc level was an independent risk factor for OSAS（OR= 6.24, 95 % CI：2.21-9.23,P〈0.01）. The hemoglobin Alc level,BMI,hypertension,age and course of diabetes mellitus were the independent risk factors for the ventilation index of OSAS. The hemoglobin Alc level was the predominant factor for OSAS. Conclusion The incidence of OSAS is high in type 2 diabetes mellitus patients. The risk of OSAS is high in type 2 diabetes mellitus patients with their blood glucose poorly controlled. OSAS is severer in obese and aged patients with a long course of diabetes mellitus accompanying hypertension.
出处
《中华老年心脑血管病杂志》
CAS
北大核心
2013年第1期29-31,共3页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
