摘要
背景接受心脏手术患者日益增加，而在心脏手术围术期的镇痛药物使用中，瑞芬太尼相对其他镇痛药物具有独特的优势，因此该药在心脏手术围术期中应用广泛。目的对有关瑞芬太尼的论著进行归纳总结，阐述其在心脏手术围术期的应用进展。内容瑞芬太尼具有独特的药物代谢动力学特点，加上其心血管的保护作用使之成为肝、肾或心功能不良患者的推荐用药。瑞芬太尼不仅在心脏手术中有对抗术中的应激刺激、加快术后恢复、提前脱离机械通气以及拔管时间等优势，也常用于心血管微创手术和经食管超声心动图等诊断性操作中。此外，瑞芬太尼可缩短心脏重症监护病房患者持续用药后气管拔管的时间。趋势瑞芬太尼在心脏手术麻醉管理中的重要性已相当明确，其在心脏手术围术期中的地位也日益突出。
Background Remifentanil has been applied in more and more cardiac operation because of several advantages not observed in other analgesics. Objective Explain the role of remifentanil used in cardiac surgical during preoperative period by summarizing articles. Content Because of the unique pharmacokinetic profile and potential protective cardiac preconditioning effect, remifentanil is recommended even in patients with renal impairment, hepatic dysfunction or poor cardiovascular function. The potential benefits of remifentanil in cardiac surgery not only include protection against intraoperative stressful stimulus, but also rapid postoperative recovery, early weaning from mechanical ventilation, and extubation. Remifentanil has also been often applied in minimally invasive cardiologie techniques or diagnostic procedures such as transesophageal echocardiography as a ideal sedative agents. Remifentanil can reduce the time to tracheal extubation after cessation of the continuous infusion in ICU. Trend Remifentanil has been proved to be essential in anesthesia management of cardiac operation, and it will play a major role in cardiac surgical preoperative period.
出处
《国际麻醉学与复苏杂志》
CAS
2013年第1期49-52,共4页
International Journal of Anesthesiology and Resuscitation
关键词
麻醉
心脏手术麻醉
重症监护
瑞芬太尼
Anaesthesia
Cardiac anaesthesia
Intensive care
Remifentanil
