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临产凝血四项检测与产时失血量的相关性研究

Research on the Relationship Between the Detection of 4 Indicators of Blood Coagulation and Blood Loss in Labor
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摘要 [目的]探讨凝血四项指标与孕妇分娩过程中出血量的关系。[方法]选择本院产科待产孕妇共2000名,分别为自然产组和剖宫产组,每组各1000例。产前用全自动血凝分析仪检测凝血四项指标:凝血酶原时间(PT),活化部分凝血酶时间(APTT),凝血酶时间(TT),纤维蛋白原(Fib)。产时由接产医师估算分娩过程中产妇出血量,分析凝血四项指标与出血量的相关性。[结果]产前凝血四项检测结果与自然分娩和剖宫产过程中出血量不相关(P〉0.05),而产前凝血四项结果异常率与产时出血量多少有明显的相关性(P〈0.05);同一孕妇四项结果异常项目越多产程大出血的几率越高。[结论]产前凝血四项结果异常率与产时出血量有一定的相关性,同一孕妇四项结果异常率与出血量明显相关,临床应给予高度重视。 [Objective] To explore the relationship between 4 indicators of blood coagulation and blood loss of pregnant women during the labor. [Methods]Totally 2000 pregnant women in obstetric department of our hospital were selected and divided into natural delivery group and cesarean section group with 1000 cases in each group. Prenatal automated coagulation analyzer was used to detect 4 indicators of blood coagulation. Maternal bleeding volume of parturients at labor was estimated by obstetricians. The relationship between ~ indicators of blood coag- ulation and blood loss was analyzed. [Results] There was no relationship between 4 indicators of blood coagulation at labor and blood loss during natural delivery and cesarean section( P ~0.05), while the abnormal rate of 4 pre- natal indicators of blood coagulation had obvious relation with intrapartum hemorrhage( P d0.05). The higher the abnormal rate of the results of 4 indicators in the same pregnant women, the higher the probability of intrapartum hemorrhage. [Conclusion]The abnormal rate of 4 parameters of prenatal blood coagulation has the certain relation with intrapartum blood loss. The abnormal rate of the results of 4 indicators is obviously correlated with blood loss in the same pregnant woman. The 4 indicators should be thought highly in clinical practice.
出处 《医学临床研究》 CAS 2012年第12期2269-2271,共3页 Journal of Clinical Research
基金 广西钦州市科技攻关项目(编号20101911).
关键词 血液凝固 分娩 出血 blood coagulation~ labor hemorrhage
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