摘要
目的探讨尿激酶联合低分子肝素钙溶栓治疗急性脑梗死的临床疗效。方法将符合治疗时间窗的急性脑梗死患者120例溶栓后随机分为两组,治疗组采用小剂量尿激酶与低分子肝素钙联用,对照组单纯用小剂量尿激酶治疗急性脑梗死进行对照研究。两组同时给予降颅压、脑细胞营养保护剂、钙离子拮抗剂等治疗。结果急性脑梗死尿激酶联合低分子肝素钙溶栓疗效优于单纯尿激酶治疗对照组,两组疗效比较差异有统计学意义(P<0.05)。结论尿激酶与低分子肝素钙两者联用治疗急性脑梗死疗效肯定,出血副作用少。
Objective To evaluate the effect of urokinase in combination with low molecular weight heparins calcium in therapy of acute cerebral infarction. Methods 120 patients with acute cerebral infarction, who were treated within 6 hours after onset of cerebral infarction diagnosed with CT,were randomLy divided into experimental group and control group.The patients in experimental group received urokinase by intravenous drip,then were given aspirin orally and low molecular weight heparins calcium by injection subcutaneously after 6 hours.The patients in control group received urokinase and aspirin. Results The difference between the two groups was significant statistically（P 〈 0.05）.The effects of urokinase in combination with low molecular weight heparins calcium in therapy of acute cerebral infarction were better. Conclusion Urokinase in combination with low molecular weight heparins calcium is safe and effective in in therapy of acute cerebral infarction.
出处
《中国医药科学》
2013年第2期71-72,共2页
China Medicine And Pharmacy
关键词
急性脑梗死
溶栓治疗
尿激酶
低分子肝素钙
Acute cerebral infarction
Thrombolytic therapy
Urokinase
Low molecular weight heparin calcium
