摘要
目的观察妇科腔镜全麻术前静注托烷司琼对患者术后恶心呕吐的影响。方法 70例ASAⅡ级的妇科腔镜全麻术患者,随机分为对照组(A组)和托烷司琼(B组),每组35例。快速麻醉诱导气管插管后机控呼吸,维持PaCO2在30～35mmHg之间。吸入异氟醚和静注维库溴铵维持麻醉与肌松。术毕时A组静脉注射生理盐水5mL,B组静脉注射托烷司琼3mg。观察每个患者用药前后生命体征与术后恶心呕吐发生率,同时记录用药后的不良反应。结果两组恶心呕吐的发生率,B组明显低于A组(P<0.05);两组患者在注药前后血压和心率的变化以及不良反应差异均无统计学意义(P>0.05)。结论妇科腔镜全麻术前静注托烷司琼降低术后恶心呕吐的发生率,对患者循环功能无明显影响,用药后眩晕、口渴、皮疹等并发症极少出现,可安全、有效地应用于临床。
Objective To study the effects of tropisetron on PONV after laparoscopy in women. Methods 70 women patients,ASA score I] ,scheduled for laparoscopy were randomly allocated into two groups：control group （group A）,group tropisetron （group B）. Normal salinel and tropisetron were given to the patients after operation respectively. The change of BP and HR,the score and the side effects of PONV were studied respectively. Results The change of BP and HR in two groups were relatively stable,the score of PONV in group B were respectively lower than those in group A（P 〈 0.05）. Two groups had minor side effects after observation（P ~ 0.05）. Conclusion Compared with normal saline, tropisetron had a better anti-PONV effect,it could be safely used in clinic.
出处
《中国医药科学》
2013年第2期75-76,共2页
China Medicine And Pharmacy
关键词
腹腔镜
妇科手术
恶心呕吐
托烷司琼
Laparoscopy
Gynecilogical operation
Nausea and vomiting
Tropisetron
