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急性冠脉综合征患者血清BNP水平与冠状动脉病变关系研究 被引量:5

Study on the relationship between serum BNP levels of patients with acute coronary ayndrome and coronary artery lesions
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摘要 目的观察不同类型ACS患者的BNP水平与冠脉病变之间的相关性。方法 121例ACS患者,分为急性ST抬高性心肌梗死组40例,急性非ST抬高性心肌梗死组43例,不稳定型心绞痛组38例,测定BNP水平。结果急性ST抬高性心肌梗死组患者BNP明显高于急性非ST抬高性心肌梗死组和不稳定型心绞痛组(P<0.01);急性非ST抬高性心肌梗死组明显高于不稳定型心绞痛组(P<0.01)。患者BNP水平比较,三支病变和双支病变均明显高于单支病变(P<0.01)。结论患者的BNP水平对ACS危险分层及病情评估具有重要的临床价值。 Objective To investigate the relationship between the brain natriuretic peptide (BNP) levels of patients with different types of acute coronary syndrome (ACS) and the coronary artery lesions. Methods A total of 121 patients with ACS were divided into the ST-elevation acute myocardial infarction (STEAMI) group with 40 patients,the non-ST elevation acute myocardial infarction (NSTEAMI) group with 43 patients and the unstable angina pectoris (UAP) group with 38 patients. Then the BNP levels were measured. Results The BNP level of the STEAMI group was significantly higher than'that of the NSTEAMI group and the UAP group (P 〈 0.01); The BNP level of the NSTEAMI group was significantly higher than that of the UAP group (P 〈 0.01). The three-vessel lesion and the two-vessel lesion were significantly higher than the single vessel lesion in the BNP level (P 〈 0.01). Conclusion The BNP level is of important clinical value to the risk stratification and condition assessment of ACS.
作者 李杰
出处 《中国医药科学》 2013年第2期121-121,135,共2页 China Medicine And Pharmacy
关键词 冠心病 脑钠肽 急性冠脉综合征 Coronary heart disease Brain natriuretic peptide Acute coronary syndrome
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