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糖化血红蛋白在糖尿病诊断中的应用价值分析 被引量:2

The Value Analysis of Glycosylated Hemoglobin in the Diagnosis of Diabetes
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摘要 目的探讨糖化血红蛋白(HbA1c)检测应用于诊断、治疗和控制糖尿病的临床价值,为糖尿病的临床诊治提供临床依据。方法选取我院70例糖尿病患者作为观察组(均按WHO糖尿病诊断标准确诊为2型糖尿病),并且选取同期健康体检者50例作为对照组,两组均采集空腹静脉血2mL,利用糖化血红蛋白仪和相关配套的试剂,严格根据标准操作程序检测HbA1c,空腹血糖(FPG)采用葡萄糖氧化酶法检测。结果观察组糖尿病患者的糖化血红蛋白(HbA1c)和空腹血糖(FPG)均明显高于对照组健康体检者(P<0.05)。结论对糖化血红蛋白(HbA1c)的检测能准确的反映血糖水平的控制情况,其临床应用对糖尿病的预防、诊断和控制均有重要价值。 Objective To observe the glycated hemoglobin(HbA1c) testing used in the clinical value of diagnosis,treatment and control of diabetes in attempt to provide the clinical basis for the clinical diagnosis and treatment of diabetes.Method Selected 70 cases of hospital patients with diabetes as the observation group(according to WHO diagnostic criteria for diabetes are diagnosed with type 2 diabetes),and selected 50 cases of healthy persons during the same period as the control group,two groups were collected for fasting blood 2mL.The use of glycated hemoglobin analyzer and related reagents,strictly in accordance with standard operating procedures for detection of HbA1c,fasting plasma glucose(FPG) using the glucose oxidase test.Results Observation group with diabetes glycated hemoglobin(HbA1c) and fasting plasma glucose(FPG) were significantly higher than healthy subjects(P0.05).Conclusion Detection of glycosylated hemoglobin(HbA1c) can accurately reflect the control of blood sugar levels and its clinical application to diabetes prevention,diagnosis and control are of great value.
作者 伍先明
出处 《中国医药指南》 2012年第36期429-431,共3页 Guide of China Medicine
关键词 糖化血红蛋白 糖尿病 空腹血糖 诊断 Glycosylated hemoglobin Diabetes Fasting blood glucose Diagnosis
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参考文献11

  • 1Ginter E,Simko V. Diabetes type 2 pandemic in 21st century[J].Bratisl Lek Lisky,2010,(03):134-137.
  • 2Shaw JE,Sicree RA,Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030[J].Diabetes Research and Clinical Practice,2010,(01):4-14.
  • 3International Diabetes Federation. The Diabetes Atlas[M].Brussels:International Diabetes Federation,2006.
  • 4Yang WY,Lu JM,Weng JP. Prevalence of Diabetes among Men and Women in China[J].New England Journal of Medicine,2010,(12):1090-1101.
  • 5戴晓灵.糖化血红蛋白在糖尿病诊治中的应用[J].检验医学与临床,2008,5(6):373-374. 被引量:50
  • 6潘长玉.2型糖尿病血糖控制的意义及实践[J].国外医学(内分泌学分册),2003,23(4):228-230. 被引量:38
  • 7American Diabetes Association. Standards of medical care in diabetes,2007[J].Diabetes Care,2007,(01):S2-S41.
  • 8陈文彬;潘祥林.诊断学[M]北京:人民卫生出版社,2008380.
  • 9Pope RM,Aps JM,Page MD. Immunologic characterization and quantification of hemoglobin A1c[J].Clinical Chemistry,1993,(02):260-263.
  • 10杨健,陈高红,杨东涛.糖化血红蛋白检测及其在糖尿病控制中的意义[J].检验医学与临床,2008,5(7):424-425. 被引量:15

二级参考文献8

  • 1孙立海,钱敏雯.糖化血红蛋白代谢变化与餐后血脂的关联比较[J].临床和实验医学杂志,2006,5(3):209-210. 被引量:7
  • 2李顺君,黄文芳,饶绍琴,董魏.糖化血红蛋白测定方法学评价[J].检验医学与临床,2007,4(5):381-381. 被引量:52
  • 3[1]Khaw KT,Wareham N,Bingham S,et al.Association of HbA1c with cardiovascular disease and mortality in adults:the European prospective investigation into cancer in Norfolk[J].Ann Intern Med,2004,141(5):413-420.
  • 4[2]Pope RM,Aps JM,Page MD,et al.Immunologic characterization and quantification of hemoglobin A1c[J].Clin Chem,1993,10(2):260-263.
  • 5[3]Stratton IM,Adler AI,Neil HA,et al.Association of glycaemia with macrovascullar complications of type 2 diabetes (UKPDS 35):prospective observational stydy[J].Br Med J,2000,321(7258):405-412.
  • 6[4]Nathan DM,Buse JB,Davidson MB,et al.Management of hyperglycemia in type 2 diabetes:a consensus algorithm for the initiation and adjustment of therapy.A consensus statement from the ADA and the European Association for the Study of Diabetes[J].Diabetes Care,2006,29(8):1963-1972.
  • 7[5]Heine RJ,Diamant M,Mbanya JC,et al.Management of hyperglycemia in type 2 diabetes[J].Br Med J,2006,333(7272):1200-1204.
  • 8[6]Yang J,Yang DT.The new clinical application of dimethyl biguanide[J].Int J Intern Med,2006,33(9):389-392.

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