摘要
目的:对人参提取物及给药后大鼠血浆进行成分的定性研究。方法:应用ABI 4000Q TRAP质谱,结合参考文献和对照品对人参提取物及入血成分进行定性研究。结果:从人参提取物中共分析鉴定了10个成分,其中根据已知对照品确定的4个化合物,推测未知的化合物6个。大鼠血浆中测定到7个化合物。结论:人参提取物中可能含有人参皂苷Rg1,Re,Rb1,Rd,Rc,Rb2,Rb3,Rf,Rg2,R0,大鼠血浆中没有测到Rf,Rg2,R0。
Objective： To obtain chemical constituent information of Ginseng extraction and its absorption in rat serum. Method： ABI 4000Q TRAP Mass was applied to determine and the compounds were analyzed with mass combined with references and standards. Result： Ten compounds in Ginseng extract and seven compounds in rat serum were identified. Conclusion： They are Rg1 , Re, Rb1 , Rd, Rc, Rb2 , Rb3 , Rf, Rg2 and Ro in Ginseng extract while ginsenoside Rf, Rg2 and R0 were not detected in rat serum.
出处
《中国实验方剂学杂志》
CAS
北大核心
2013年第2期148-153,共6页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家自然科学基金项目(81102795)
国家中医药管理局课题(06-07ZP49)
关键词
人参
定性
液质联用
Ginseng Radix et Rhizoma
qualitative analysis
LC-MS/MS
