摘要
目的研究反流性食管炎(RE)中医证型及舌象与胃镜下表现的相关性。方法对102例符合入选条件的RE患者的流行病学信息、中医证型、舌象及食管黏膜胃镜下表现进行观察和分析。结果在102例RE患者中,病程较短者以热证、实证多见,病程长者以虚证多见,不同病程的RE患者中医证型分布差异具有统计学意义(P<0.05)。RE胃镜下分级为Ⅰ级的患者多为肝胃郁热、脾胃湿热、肝胃不和证,Ⅱ级者多为脾胃湿热及脾胃虚弱证,Ⅲ级者以脾胃虚弱及胃阴不足证为主,不同中医证型的胃镜下分级的差异有统计学意义(P<0.01)。幽门螺杆菌(Hp)阳性的RE患者在脾胃湿热及肝胃郁热证型中分布较多,不同中医证型的Hp感染的差异有统计学意义(P<0.05)。食管黏膜粗糙不平的RE患者以淡红舌多见,其他食管黏膜各损伤类型均以红舌常见,食管黏膜充血、水肿、糜烂、渗出物增多均以薄黄苔多见,黏膜粗糙不平以白腻苔多见,舌象与食管黏膜表现分布差异具有统计学意义(P<0.05)。结论 RE中医证型与病程、胃镜下表现、Hp感染之间以及RE舌象与食管黏膜表现之间存在一定的相关性。
Objective To study the relationship between TCM syndrome types,tongue signs and gastroscopic manifestation of reflux esophagitis(RE).Methods The epidemiologic messages,TCM syndrome types,tongue signs and the gastroscopic manifestation of 102 RE patients were observed and analyzed.Results Patients with short-term course mainly showed heat and sthenia syndrome,while asthenia syndrome was common in long-lasting course.The TCM syndrome distribution was statistically significant different between RE patients with different disease courses(P〈0.05).RE can be classified into three grades according to the gastroscopic manifestation with statistically significant difference(P〈0.01).Grade Ⅰ was mainly in type of stagnant heat in liver and stomach,spleen-stomach damp-heat,disharmony of liver and stomach.Grade Ⅱ was mainly in the type of spleen-stomach damp-heat,weakness of the spleen and the stomach.Grade Ⅲ was usually in the type of weakness of the spleen and the stomach,deficiency of stomach Yin.More Hp-positive patients attributed to spleen-stomach damp-heat and stagnant heat in liver and stomach,Hp infection in different TCM syndrome type was significantly different(P〈0.05).Hackly surface of esophageal mucosa was often associated with light red tongue,and RE patients with all the other esophageal mucosa damage types tend to had red tongue.Esophageal mucosal hyperemia,edema,erosion and over-effusion were often associated with thin yellow moss.Hackly surface was often associated with white greasy moss.The mucous membrane performance of tongue manifestation was significantly different(P〈0.05).Conclusion There is relationship between TCM syndrome type,disease course,Hp infection and endoscopic grades.There is relationship between tongue signs and mucous membrane performance.
出处
《中国中医药信息杂志》
CAS
CSCD
2013年第1期22-24,共3页
Chinese Journal of Information on Traditional Chinese Medicine
关键词
反流性食管炎
中医证型
舌象
胃镜
相关性
reflux esophagitis
TCM syndrome type
tongue sign
gastroscope
correlation