期刊文献+

孟鲁斯特钠治疗老年性变异性哮喘和气道炎症的疗效 被引量:15

下载PDF
导出
摘要 变异性哮喘是老年患者常见的一种疾病,由于该年龄段的人群大多体质较弱,气管和肺部受外界空气影响,极易感染形成分泌物,造成水肿或者呼吸肌肉痉挛,引发更严重的病变。白三烯(LT)在哮喘发生、发展的多个环节发挥重要作用,其水平无论在急性发作期还是缓解期均高于正常人。LT受体拮抗剂能够选择性结合LT受体,减轻器官对¨的反应程度,从而达到治疗哮喘的目的。本研究拟探讨孟鲁斯特钠的临床疗效以及安全性。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2013年第2期407-408,共2页 Chinese Journal of Gerontology
  • 相关文献

参考文献7

  • 1Potter-Perigo S, Baker C. Regulation of proteoglycan synthesis by leukot- rieue D4 and epidmnal growth factor in bronchial smooth muscle cells [ J. Am J Respir Cell Mol Biol,2004 ;30( 1 ) :101-8.
  • 2王建平,鲁德玗,杨燕.孟鲁斯特用于稳定期慢性阻塞性肺疾病患者疗效观察[J].山东医药,2007,47(5):41-42. 被引量:10
  • 3Mitsuta K, Shimoda T, Fukushima C, et al. Preoperative steroid therapy inhibits cytokine production in the lung parenchyma in asthmatic patients J3. Chest,2001 ;120(4) :1175-83.
  • 4Steinshamn S, Sandsund M, Sue-Chu M, et al. Effects of montelukast on physical performance and exercise economy in adult asthmatics with exer- cise-induced broncho-constriction(J3. Seand J Med Sei Sports,2002 ; 12 (4) :211-7.
  • 5Zhang J,Yu C, Noonan G,et al. Effect of montelukast, a once-daily leu- kotriene receptor antagonist, on peak expiratory flow variability[ J 3. Clin Ther, 2002 ; 24 (4) : 574 -82.
  • 6Ngmphaiboon J. Montelukast in general pediatric practices [ J 3. Med As- see Thai,2005 ;88(4) :348.
  • 7Bonville CA, Rosenberg HF, Domaehowske JB. Ribavirin and eysteinyl- leukortriene-1 receptor blockade as treatment for severe bronehiolitis [ J 1. Antiviral Res,2006 ;69 (2) :53.

二级参考文献9

  • 1路明,姚婉贞.吸入糖皮质激素在慢性阻塞性肺疾病稳定期中的应用[J].国外医学(呼吸系统分册),2005,25(6):473-477. 被引量:7
  • 2Lacoste JY,Bousquet J,chanez P,et al.Eosinophilic and neutrophilic inflammation inasthma,chronic bronchitis,and chronic obstructive pulmonary disease[J].Allergy Clin Immunol,1993,92(4):537-548.
  • 3Birke FW,Meade CJ,Anderskewitz R,et al.In vitro and vivo pharmacological characterization of BⅢ284,A novel and potent leukotriene B4,receptor antagonist[J].Pharmacol Exp Ther,2001,297(7):458-466.
  • 4Crooks SW,Bayley DL,Hill SL,et al.Bronchial inflammation in acute bacterial exacerbations of chronic bronchitis:the role of leukotriene B4[J].Eur Respir J,2000,15(2):274-280.
  • 5Piperno D,Pacheco Y,Hosni R,et al.Increased plasma levels of atrial natriuretic factor,renin activity,and leukotriene C4 in chronic obstructive pulmonary disease[J].Chest,1993,104(2):454-459.
  • 6Mitsunobu F,Mifune T,Hosaki Y,et al.Enhanced production of leukotrienes by peripheral leukocytes and specific IgE antibodies in patients with chronic obstructive pulmonary disease[J].Allergy Clin Immunol,1996,107(3):492-498.
  • 7Ronchi MC,Piragino C,Rosi E,et al.Role of sputum differential cell count in detecting airway inflammation in patients with chronic bronchial asthma or COPD[J].Thorax,1996,51(10):1000-1004.
  • 8Pinar C,Aysin S,Yavuz H,et al.Short-term effects of montelukast in stable patients with moderate to severe COPD[J].Respiratory Medicine,2006,99(7),444-450.
  • 9慢性阻塞性肺疾病诊治指南[J].中华结核和呼吸杂志,2002,25(8):453-460. 被引量:5103

共引文献9

同被引文献125

引证文献15

二级引证文献92

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部