摘要
目的探讨3.0T磁共振弥散加权成像的表观弥散系数(ADC)在乏脂肪肾血管平滑肌脂肪瘤(RAML)与T1a期肾透明细胞癌(CCRCC)鉴别诊断中的价值。方法回顾性分析经病理证实的11例乏脂肪RAML及16例T1a期CCRCC患者的常规MR表现、化学位移成像及ADC值,两个不同类型肿瘤的ADC值比较采用独立样本t检验,并作ROC曲线分析。结果乏脂肪RAML的平均ADC值为(1.062±0.131)×10-3 mm2/s,明显大于T1a期CCRCC的(0.742±0.137)×10-3mm2/s(P<0.01)。ROC曲线下面积为0.949,以0.881×10-3 mm2/s为最佳鉴别阈值,其诊断乏脂肪RAML的敏感性为90.9%,特异性为87.5%。结论 ADC值有助于乏脂肪RAML与T1a期CCRCC的鉴别诊断。
Objective To evaluate the value of apparent diffusion coefficient(ADC) at 3.0T MR in differentiating renal angiomyolipoma (RAML) absent of fat from pTla clear cell renal cell carcinoma(CCRCC). Methods Conventional MR images, chemical shift imaging and ADC values of 11 cases with RAML absent of fat and 16 cases of pTla CCRCC confirmed pathologically were retrospectively analyzed. The comparison of ADC values of two different types of tumors was performed with Student's t-test and the ROC curve was performed to evaluate the diagnostic efficiency of ADC values. Results The mean AIX; value of RAML absent of fat was (1. 062±0. 131) ×10^-3 mm^2/s, which was significantly higher than (0.742 ±0.137)×10^-3 mm^2/s of pTla CCRCC (P〈0. 01). The area under the ROC curve was 0. 949. Taking 0. 881 ×10^-3 mm^2/s as the best differential threshold of AIX; value, the sensitivity and specificity of diagnosing RAML absent of fat were 90.9% and 87.5 %, respectively. Conclusion The ADC value is helpful in differentiating RAML absent of fat from pTla CCRCC.
出处
《江苏医药》
CAS
北大核心
2013年第1期62-65,F0003,共5页
Jiangsu Medical Journal