摘要
目的:研究黄芪颗粒联合维生素C辅助治疗小儿病毒性心肌炎的治疗效果。方法:将104例病毒性心肌炎患儿随机分为观察组和对照组各52例。两组均采取抗病毒、营养心肌及免疫调节等常规治疗,观察组加用黄芪颗粒每天2次冲服联合维生素C 20mg/kg治疗,两组患儿均治疗14d。观察两组患儿临床疗效、心肌酶谱各项指标改善情况及症状、体征、心电图、心肌酶恢复正常时间。结果:观察组总有效率92.3%,高于对照组的73.1%(χ2=5.675,P<0.01);治疗后两组心肌酶谱各指标均下降,但观察组下降更明显,两组比较差异有统计学意义(P<0.05);观察组各项指标恢复正常时间显著少于对照组,两组比较差异有统计学意义(P<0.05)。结论:黄芪颗粒联合维生素C辅助治疗小儿病毒性心肌炎能提高疗效,缩短病程,值得临床推广应用。
Objective： To study the effects of astrgalus granules combined with vitamin C as adjuvant treatment for infantile viral myocarditis. Methods： One hundred and four cases c,f viral myocarditis were randomly divided into an observation group （52 cases） and a control group （52 cases）. The two groups received conventional treatment such as antivirals, myocardial nutritional medications and immune modulators. The observation group was treated with astragalus granules combined with vitamin C 20 mg/kg twice a day, both groups were treated for 14 days. Therapeutic effects, myocardial enzyme spectrum, the improvements of symptoms, signs and other indicators were observed. Results： The total efficiency of the observation group was 92.3% , which was better than that of the control group （73.1% ） （P〈0.01）. After treatment, myocardial enzyme spectrum of the observation group had significant differences compared with the control group （P〈0.05）. There was a difference between both groups in the recovery time of each parameter （P〈0.05）. Conclusions： Astragalus granules combined with vitamin C in the treatment of viral myocarditis in children can improve the curative effect, shorten the course of disease, and be suitable for clinical application.
出处
《儿科药学杂志》
CAS
2013年第2期13-15,共3页
Journal of Pediatric Pharmacy
关键词
黄芪颗粒
维生素C
小儿
病毒
心肌炎
Astragalus granules
Vitamin C
Children
Virus
Myocarditis
