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七氟醚麻醉对颅内肿瘤患儿围术期血浆内皮素及一氧化氮水平的影响 被引量:4

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摘要 目的分析七氟醚麻醉对颅内肿瘤患儿围术期血浆内皮素(ET)及一氧化氮(NO)的影响。方法将实施手术治疗的48例颅内肿瘤患儿随机分为两组,氯胺酮组23例采用氯胺酮行麻醉维持,七氟醚组25例采用七氟醚行麻醉维持;观察两组术中ET及NO水平变化。结果麻醉诱导前(T1)、术毕(T5)时两组血浆ET、NO水平差异不显著(P>0.05);气管插管后(T2)、切开颅脑时(T3)及术中(T4)七氟醚组血浆ET、NO水平均低于氯胺酮组(P<0.01)。结论七氟醚在小儿颅内肿瘤手术中可抑制血浆ET、NO的生成,保护脑功能。
作者 冯正举
出处 《白求恩军医学院学报》 2013年第1期27-28,共2页 Journal of Bethune Military Medical College
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