摘要
目的:评价氯地松乳膏治疗皮炎湿疹类皮肤病的疗效。方法:研究181例于我院门诊及住院部明确诊断为皮炎湿疹类皮肤病的患者,随机分为治疗组与对照组,给予患者相同外形、颜色、包装的氯地松乳膏(含地塞米松0.025%、氯霉素1%)及对照药物尿素乳膏,使用3周后比较2组疗效。结果:治疗组与对照组的有效率分别为78.57%、4.82%(P<0.001)。与对照组比较,治疗组患者症状改善明显。治疗组有3例出现给药部位皮肤发红及瘙痒感,1例出现给药部位毛发增粗,未发现其他全身或局部不良反应。结论:氯地松乳膏治疗皮炎湿疹类皮肤病安全、有效。
OBJECTIVE： To evaluate therapeutic efficacy of Choramphenicol dexamethasone ointment （0.025% dexametha- sone, 1% choramphenicol） in the treatment of dermatitis and eczema. METHODS： 181 out-patient and inpatient patients of our hospital diagnosed as dermatitis and eczema were divided into treatment group and control group randomly. All patients were given same package of Choramphenicol dexamethasone ointment or urea cream with same appearance and color and control. Therapeutic efficacies of dermatitis and eczema were observed and compared after 3 weeks of treatment. RESULTS： The effective rates were 78.57% in treatment group and 4.82% in control group （P〈0.001）. Compared with control group, the symptoms were improved significantly in treatment group. In treatment group, 3 patients suffered from redness and itching of delivery site, and hair enlarge- ment of delivery site was found in 1 patient; no systemic or local ADR was found. CONCLUSION： Choramphenicol dexametha- sone ointment is safe and effective for dermatitis and eczema.
出处
《中国药房》
CAS
CSCD
2013年第6期532-533,共2页
China Pharmacy
关键词
皮炎
湿疹
氯地松乳膏
疗效
安全性
Dermatitis
Eczema
Choramphenicol dexamethasone ointment
Therapeutic efficacy
Safety
