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Th17与毛细支气管炎的研究进展 被引量:7

Advancement of T helperl7 cells in bronchiolitis
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摘要 毛细支气管炎(毛支)是2岁以下小儿常见的下呼吸道感染性疾病,主要病原体是呼吸道合胞病毒,是需住院治疗的常见呼吸道疾病,且与哮喘的发病密切相关。目前毛支的发病机制尚未完全阐明,近年来发现T辅助性17细胞(Th17)在其发病中占有重要地位。该文就近年来对Th17在毛支发病机制方面的研究进展作一综述。 Bronchiolitis is a common lower respiratory infection disease in children younger than two years old. The main pathogen of bronchiolitis is respiratory syncytial virus, which is also associated with the asth-ma. By now,it is still unknown about the pathogenesis of bronchiolitis. Recent findings provide that T helper17 ( Th17 ) cells play an important role in bronchiolitis. This review summarizes the progresses of regulation of Th17 cells development,Th17 cells function, and the relationship between Th17 cells and bronchiolitis.
出处 《国际儿科学杂志》 2013年第1期18-21,共4页 International Journal of Pediatrics
关键词 毛细支气管炎 T辅助性17细胞 呼吸道合胞病毒 Bronchiolitis T helperl7 cell Respiratory syncytial virus
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