摘要
妊娠甲状腺功能异常是妊娠的高危因素，临床前瞻性观察和动物实验研究均表明妊娠早期亚临床甲状腺功能减退症能够导致后代智力受损，及时诊断和有效的治疗有可能预防这些危害。所以，应倡导对所有孕妇在妊娠早期进行甲状腺功能筛查，最好在妊娠8周以前。母体甲状腺生理性变化为妊娠期甲状腺疾病的诊断和治疗带来困惑，因此，需要确立妊娠特异性的正常参考范围。影响正常人群甲状腺功能相关指标测定值的因素包括所在地区的碘营养状态和检测试剂，所以建议各个地区和医院建立自己的参考值。（手华检验医学杂志，2013，36：36-39）
Abnormal thyroid function is high risk for pregnancy. Studies from clinical observation and animal experiments have indicated that maternal sub clinical hypothyroidism during the first gestational term may lead to impairment of brain development of offspring, and early diagnosis and effective treatment may prevent the damage. Therefore, it is suggested that screening thyroid function before gestational 8 weeks in pregnant women is initiated. The changes in thyroid function during pregnancy are related to these changes in maternal thyroid physiology can lead to confusion in the diagnosis or evaluation of thyroid abnormalities. Establishment of trimester-specific reference ranges is urgently needed. Local iodine nutritional statue and testing reagent effect the measured value of thyroid function in general population, so it is recommend that all regions and hospitals should establish their own pregnancy reference ranges.
出处
《中华检验医学杂志》
CAS
CSCD
北大核心
2013年第1期36-39,共4页
Chinese Journal of Laboratory Medicine
