摘要
目的:探讨可疑性原发性房角关闭(primary angle closure suspect,PACS)、原发性房角关闭(primary angle closure,PAC)及原发性闭角型青光眼(primary angle-closure glaucoma,PACG)解剖结构的异同。方法:采用国际区域性流行病学眼科学会(International Society of Geographical and Epidemiological Ophthalmology,ISGEO)的分类系统,分为4组:正常对照组(47例47眼)、PACS组(157例157眼),PAC组(96例96眼)及PACG组(86例86眼)。应用NIDEK Echoscan US-1800型A型超声测量系统对被测者眼部解剖结构(前房深度、晶状体厚度、眼轴长度、晶状体相对位置)进行测量,各项均值进行组间差异比较。结果:正常人、PACS和PAC与PACG的年龄、晶状体厚度依次增高(P<0.05),前房深度、晶状体相对位置依次递减(P<0.05);与正常人相比,PACS和PAC与PACG除眼轴外其余的参数都有差异(P<0.05);与PACG相比,正常人、PACS和PAC的解剖结构参数都存在差异(P<0.05);但PAC与PACG两组相比,除前房深度、晶状体相对位置外,其余的各项解剖参数相比无统计学意义(P>0.05)。结论:从正常人、PACS、PAC到PACG的前房深度变浅、眼轴变短、晶状体相对位置靠前。前房深度、晶状体相对位置对PACG的早期诊断及预防有一定的临床价值。
AIM: To discuss the anatomical structure of the patients with normal group, primary angle closure suspects (PACS), primary angle closure (PAC) and primary angle- closure glaucoma (PACG). METHODS: All persons were divided into four groups according International Society of Geographical and Epidemiological Ophthalmology (ISGEO) classification methods: normal group, PACS group, PAC group, PACG group. Anatomical structures including the anterior chamber depth ( ACD), lens thickness ( LT), the axial length (AL) and relative location of lens (RLL) were measured by a contact ultrasound A- scan biometry device (NIDEK, Echoscan US-1800) in 47 eyes of 47 normal persons, 157 eyes 157 of patients with PAC, 96 eyes of 96 patients with PAC and 86 eyes of 86 patients with PACG. RESULTS: The age , LT were gradually increased from PACS, PAC to PACG, but the ACD, RLL gradually were decreased(P〈0.05). There were significant differences in ACD, LT and RLL between normal group and other groups (P〈0.05). ALL anatomical items were different between PACG and other groups(P〈0.05). Compared with PAC, PACG had significant differences in ACD and ALL (P〈 0.05), but other items had no difference. CONCLUSION: The anatomical characteristics graduallyprogress from PACS, PAC to PACG. The ACD, RLL can be an indicator in clinical practice for earlier PACG diagnosis.
出处
《国际眼科杂志》
CAS
2013年第2期367-369,共3页
International Eye Science