摘要
目的探讨单唾液酸四己糖神经节苷脂钠治疗突发性耳聋的疗效。方法将突发性耳聋患者80例随机分为治疗组和对照组,治疗组患者给予单唾液酸四己糖神经节苷脂钠静滴,对照组患者给予甲钴胺注射液静推,两组均同时行激素、扩血管药物、高压氧等治疗。10 d为一疗程。结果单唾液酸四己糖神经节苷脂钠组听力提高的总有效率为85%,痊愈率为52.5%;而对照组的总有效率为62.5%,痊愈率为27.5%,两组差异有统计学意义(P<0.05);治疗组耳鸣好转的总有效率为80%,对照组的总有效率为51.7%,两组差异有统计学意义(P<0.05)。结论单唾液酸四己糖神经节苷脂钠治疗突发性耳聋疗效相对于其他方法疗效较好。
Objective To investigate the efficacy of monosialotetrahexosylganlioside in the treatment of sudden hearing lossl. Methods 80 cases suffered from sudden heating loss were randomly divided into 2 groups. Except for glucocor- ticoid plus vasodilators and hyperbaric oxygen therapy, 40 cases in the treatment group were administrated with mono- sialotetrahexosylganlioside, while the other 40 cases in the control group were given mecobalamin injection. One course lasted for 10 days. Results The total effective rates of hearing improvement between the treatment group and control group were 85% and 62.5%, while the cure rates of both groups were 52.5% and 27.5% （ P 〈 0.05 ）. Meanwhile, the total effective rate of tinnitus in the treatment and control group were 80% and 51.7% （ P 〈 0.05 ）. Conclusion Monosialotetrahexosylganlioside plays a positive role in the treatment of sudden heating loss.
出处
《山东大学耳鼻喉眼学报》
CAS
2013年第1期24-25,30,共3页
Journal of Otolaryngology and Ophthalmology of Shandong University
