摘要
目的通过嗜酸乳杆菌联合标准三联方案5周疗法,探讨嗜酸乳杆菌对提高三联方案幽门螺杆菌(Helicobacter pylori,H.pylori)根除率的作用。方法分析我院消化内科门诊H.pylori阳性初治患者134例临床资料。将134例患者分为治疗组和对照组,治疗组采用嗜酸乳杆菌+标准三联方案5周疗法,对照组采用标准三联方案1周疗法。结果所有患者均按时完成治疗,完成随访的117例患者中,治疗组61例,治愈53例,治愈率86.9%;对照组56例,治愈40例,治愈率71.4%;两组比较有统计学差异(P<0.05)。结论嗜酸乳杆菌能提高三联方案H.pylori根除率,患者服药副作用小,依从性好,具有应用价值。
Objective To evaluate the clinical value of eradicating Helicobacter pylori by lactobacillus acidophilus for 5 weeks combined with proton pump inhibitors. Methods 134 previously untreated H. pylori-positive patients were selected in the gastroenterology clinic of our hospital. All patients were randomly divided into treatment group and control group. The medicine containing lactobacillus acidophilus was taken in treatment group from the first week to the five weeks. And the PPI three-drug regimen was added in the third week. The control group was treated by only PPI threedrug regimen. Results All patients accomplished the therapy in plan. The cure rates were 86.9% （53/61） in treatment group and 71.4% （40/56） in the control group. There was statistically significant difference between the treatment group and the control group （P 〈 0.05）. Conclusion The method of the lactobacillus acidophilus combined with proton pump inhibitors is a regimen with higher efficacy and lower toxicity.
出处
《胃肠病学和肝病学杂志》
CAS
2013年第2期133-134,共2页
Chinese Journal of Gastroenterology and Hepatology
关键词
幽门螺杆菌
嗜酸乳杆菌
质子泵抑制剂
治愈率
Helicobacter pylori
Lactobacillus acidophilus
Proton pump inhibitors
Cure rate
