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2型糖尿病的胰岛素治疗 被引量:2

Insulin therapy in type 2 diabetic patients
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摘要 糖尿病是一种慢性、进展性疾病,随着2型糖尿病的进展,胰岛B细胞数量和功能逐渐衰竭。根据UKPDS研究,2型糖尿病患者的血糖达到诊断糖尿病标准时,B细胞的功能已丧失50%,随着病程延长,胰岛细胞功能逐年减退。因此,2型糖尿病的治疗不仅要改善胰岛素抵抗,还要阻止胰岛B细胞功能的衰竭。胰岛素既能控制血糖又能保护胰岛B细胞功能,在糖尿病治疗中发挥重要作用。当机体内源性胰岛素分泌不足时,必须及时开始胰岛素治疗以达到目标血糖水平,进而减缓糖尿瘸慢性并发症的发生和发展。
作者 齐琪 母义明
出处 《药品评价》 CAS 2012年第31期16-18,22,共4页 Drug Evaluation
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参考文献15

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