摘要
目的研究中药北刘寄奴(Siphonostegia chinensis Benth.)的化学成分。方法采用正相硅胶、反相ODS、Sephadex LH-20等柱色谱及高效液相色谱等手段进行分离纯化,并通过理化性质与光谱分析鉴定化合物的结构。结果从北刘寄奴体积分数为95%的乙醇提取物中分离了6个苯乙醇苷类单体成分,分别鉴定为去咖啡酰基类叶升麻苷(decaffeoylverbascoside,1)、acteoside(2)、isoacte-oside(3)、crenatoside(4)、β-oxoacteoside(5)和syringalide A 3'-α-L-rhamnopyranoside(6)。结论其中化合物1、3～6为首次从阴行草属中分离得到。
Objective To study the chemical constituents from whole plant of Siphonostegia chinensis Benth. Methods The compounds were isolated by chromatographic methods such as silica gel, ODS, Sephadex LH- 20 and HPLC, and identified by the chemical and physical methods, especially spectral analysis. Results Six phenylethanoid glycosides were isolated. The structures of them were identified as decaffeoylverbascoside （ 1 ）, acteoside （ 2 ）, isoacteoside （ 3 ）, crenatoside （ 4 ）, fl-oxoacteoside （ 5 ）, and syringalide A 3 ＇-t^-L-rham- nopyranoside（6）. Conclusions Among them,1 and 3-6 are obtained from Siphonostegia genus for the first time.
出处
《沈阳药科大学学报》
CAS
CSCD
北大核心
2013年第2期95-99,共5页
Journal of Shenyang Pharmaceutical University
基金
国家自然科学基金资助项目(81173524)
天津市科委自然科学基金资助项目(10ZCKFSY09300)
国家科技重大专项项目-重大新药创制资助项目(2011ZX09307-002-01)
关键词
阴行草属
北刘寄奴
苯乙醇苷
化学成分
结构鉴定
Siphonostegia
Siphonostergia chinensis Benth.
phenylethanoid glycoside
chemical constitu-ent
structure identification
