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应用CT与CT-MRI融合图像勾画恶性胶质瘤术后靶区的差异 被引量:11

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摘要 目的研究CT-MRI融合技术在勾画恶性胶质瘤术后肿瘤大体体积(GTV)中的作用。方法收集30例均有明确病理诊断的恶性胶质瘤术后病例,其中星形细胞瘤Ⅲ级28例,胶质母细胞瘤2例。由5位5年以上工作经验的肿瘤放射治疗医师勾画30例恶性胶质瘤术后靶区,实验分为两组:CT组为5位医师分别在参考患者术后MRI片基础上在CT定位图像上勾画术后靶区GTV;CT-MRI组为5位医师在CT-MRI融合图像上勾画术后靶区GTV;分别测定两组靶区体积并比较其差异及两组各医师之间变异程度。结果两组所勾画术后靶区GTV差异明显,且CT-MRI组所勾画GTV较小,差异有统计学意义(P<0.05);CT组各医师所勾画靶区体积变异系数明显大于CT-MRI组。结论应用CT-MRI融合图像勾画恶性胶质瘤术后靶区较单纯利用CT定位图像上勾画术后靶区GTV小,有望减少正常脑组织受照体积并提高靶体积剂量;应用CT-MRI融合图像勾画恶性胶质瘤术后靶区可以减少不同医师之间的差异,提高靶区勾画准确性。
出处 《广东医学》 CAS CSCD 北大核心 2013年第1期90-92,共3页 Guangdong Medical Journal
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参考文献13

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