摘要
目的回顾性分析患者术前甲状腺球蛋白（TG）及甲状腺球蛋白抗体（TGAb）的水平，探讨其在结节性甲状腺肿和甲状腺癌的鉴别诊断意义。方法选取2006年1月至2007年1月承德市中心医院普外科180例分化型甲状腺癌（differentiated thyroid carcinoma，DTC）为A组，150例结节性甲状腺肿为B组，健康人120例为对照组（C组）。所有入选对象均行甲状腺超声、甲状腺功能及甲状腺CT检查。结果A组TG和TGAb分别为40．0％和43．3％显著高于B组7．33％和9．33％及C组4．17％和7．50％，A组与B、C组之间差异有统计学意义（P〈0．05），但B组与C组差异无统计学意义（P〉0．05）。结论TG及TGAb测定在结节性甲状腺肿和甲状腺癌的鉴别诊断上有临床意义。
Objective To investigate the clinical significance of thyroglobulin（TG） and thyroglobulin antibody （TGAb）in differential diagnosis between nodular goiter and differentiated thyroid carcinoma（ DTC ）. Meth- ods From Jan. 2006 to Jan. 2007, 180 cases of thyroid carcinoma were included in group A（male：45, average age ：47 ; female ： 135, average age ： 43） and 150 cases of nodular goiter were included in group B（ Male ：55, average age 43; female：95, average age：41 ）. All the cases came from the General Department of Chengde Central Hospital. Group C （ the control group） included 120 cases （ male ： 40, average age ： 38 ; female ： 80, average age ： 44 ）. All patients underwent thyroids ultrasound, thyroid function detection and CT. Results The positive rate of TG and TGAb was 40. 0% and 43.3% in group A, which were obviously higher than those in group B （7. 33%, 9. 33% ）and group C （4. 17%, 7. 50% ）. The difference had statistical significance （P 〈 0. 05 ）. However, there was no statistical difference between group B and group C （P 〉 0. 05）. Conclusion The measurement of TG and TGAb has clinical significance in differential diagnosis between DTC and nodular goiter.
出处
《中华内分泌外科杂志》
CAS
2013年第1期54-55,68,共3页
Chinese Journal of Endocrine Surgery
